Low testosterone and arthritis – is there a link?

Jan 18, 2024

More than 53 million people in the U.S. have arthritis, which involves joint pain, swelling, and stiffness. Anyone can develop arthritis, especially if they’re over age 50, but other factors may contribute — research shows that low testosterone may be one of them.

A recent study published in Scientific Reports found a possible connection between low testosterone and an increased risk of developing arthritis. After analyzing data from more than 10,000 men and women, researchers found that adults with arthritis had significantly lower testosterone levels than those without arthritis. Not only that, but those with lower testosterone levels were said to be at higher risk for developing arthritis.

So does this mean low testosterone causes arthritis? Not exactly.

Despite the interesting correlation between low testosterone and arthritis, the study authors make clear that their research does not mean low testosterone causes arthritis. Their research provides insight into the relationship between hormonal health and joint health, but a lot more research is needed to better understand the link between these two conditions.

We know that there are a number of different factors that can make someone more likely to develop arthritis. These vary depending on the type of arthritis, but can include things like joint injuries, being overweight, and genetics. In the study published in Scientific Reports, the researchers point out several shared risk factors for arthritis and low T. These include:

  • Obesity
  • Advanced age
  • Smoking
  • Diabetes
  • Hypertension

More on the relationship between testosterone and joint health

Earlier research has shown that sex hormones like testosterone are directly involved in important bodily processes like bone formation. Sex hormones may also help protect against cartilage inflammation and breakdown, which are common with arthritis. Research also shows that low testosterone triggers the production of a substance called RANKL that may lead to decreased bone density.

Tips for improving arthritis

Remember — low testosterone doesn’t necessarily cause arthritis, but this new research shows that it may increase the risk. People can develop arthritis for many different reasons, like joint injuries and overuse, obesity, and smoking.

Only you and your doctor can decide the best path forward for treating arthritis, but there are some things you may be able to do at home as a starting point. While you can’t control your age or genetics, there are lifestyle changes that may increase testosterone and improve symptoms of arthritis at the same time. These include:

  • Maintaining a healthy weight
  • Following a nutritious diet and exercising regularly
  • Prioritizing sleep
  • Giving up smoking
  • Cutting back on drinking
  • Lowering your stress levels

Some important takeaways:

  • Low testosterone doesn’t necessarily cause arthritis, but it may be associated with an increased risk.
  • Testosterone is directly involved in bone formation and mineralization, and protects cartilage from inflammation and degradation.
  • Lifestyle changes that may improve arthritis and low testosterone include maintaining a healthy weight, exercising regularly, giving up smoking, and managing your stress levels.
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